ODYSSEY-HCM Phase 3 Enrollment Complete (nHCM)
Procedural milestone: enrollment finishes for the Phase 3 trial of CAMZYOS in non-obstructive HCM. Anchors the Q2 2027 readout date.
What’s at stake
CAMZYOS (mavacamten) is a first-in-class oral cardiac myosin inhibitor developed by Bristol Myers Squibb that treats hypertrophic cardiomyopathy (HCM) — a genetic condition in which the heart muscle thickens abnormally and obstructs blood flow. The drug reduces the number of myosin-actin cross-bridges that form during each heartbeat, decreasing the force of contraction and relieving the outflow obstruction that causes breathlessness, chest pain, and syncope. CAMZYOS is approved for symptomatic obstructive HCM and is being studied in non-obstructive HCM — a distinct phenotype with twice the patient population and no approved drug therapy — in an ongoing Phase 3 trial.
No primer in glossary yet.
Prior BMY reactions to Enroll. events
| Date | Headline | Outcome | 1W | 1M | 6M |
|---|---|---|---|---|---|
| Jan 2026 | CAMZYOS — Pivotal Enrollment Complete | positive | +5.3% | +3.9% | +6.1% |
Disclosure trail
- Apr 22, 2026·8d agopinned · highest confidenceHIGH confPRMONTHtop claimJUN2026
“ODYSSEY-HCM, the Phase 3 study of CAMZYOS in non-obstructive HCM, is expected to complete enrollment in June 2026.”
conf 88%via llm